"Buffett once told me there are three 'I's in every cycle. The 'innovator,' that's the first 'I.' After the innovator comes the 'imitator.' And after the imitator in the cycle comes the idiot." -Theodore Forstmann, quoting Warren Buffett
Tuesday, September 23, 2008
Saturday, September 13, 2008
Ownership vs markets - Stumbling and Mumbling
Summary:
Chris Dillow argues that the traditional capitalist ownership structure is responsible for the credit crunch, not free markets as others have argued. Banks lost money on mortgage derivatives because of principal-agent failings, i.e. bosses (principals) don't know what the traders (agents) are doing. Traders have an incentive to take risk: life-changing bonus; gains exceeds benefits of prudence. Also, little pressure upon banks' executives to be prudent because when shareholding is dispersed, no individual shareholder has much incentive to rein in management. There has been more "bad" financial innovation that good ones. With good financial innovation it is very difficult for anyone to own its beneficial effects, it's a public good. Gains from “bad” financial innovation are more appropriable, hence we get more of it. Finally, banks' reluctance to lend to each other stems from the inability of management of such complex organisations to know everything. Banks should become more like venture capitalists, i.e. using an internal market, allocating capital to semi-independent divisions, which put in their own capital. (Published: 12/09/08)
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Thursday, July 31, 2008
Quote of the Day
“When the facts change, I change my mind – what do you do, sir?” - John Maynard Keynes
There is hope yet for science park toilers - FT.com
Summary:
Jonathan Guthrie sees evidence that the level of innovation in the UK appears to be declining. Not much coming out of universities anymore. We're living through a fallow period for innovation, fundamental innovation is slowing up after a remarkable 40 year boom. Internet investment bubble, Schumpeterian explanation: copycats to pile in on the upswing of an innovation wave. Was a fiasco for VC investment in UK. Returns negative for average fund set up after 1996 over 5 to 10 year periods. Confidence has weakened further with the credit crunch, which has closed the market for flotations. Less money was invested in European technology start-ups last quarter than at any time since 2001. Venture capital is more fragile this side of the Atlantic than in the US. Technology investment in UK will probably recover. VCs need to market themselves, focus on the lofty top decile, not the mediocre median. Early stage technology investment is attractive as a way to lay small bets on risky, glamorous propositions. Also need a handful of breakthroughs that are immensely remunerative. Biotech lost cost. Renewable energy and power savings big hope. (Published: 30/07/08)
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Wednesday, July 30, 2008
Quote of the Day
"Spreadsheets are easy; science is hard." - Shaywitz and Taleb
Shaywitz and Taleb in answer to the question "Why do pharmaceutical companies, which spend billions of dollars each year trying to turn advances into treatments, have so little to show for their efforts?"
Drug research needs serendipity - FT.com
Summary:
David Shaywitz and Nassim Taleb write that the pharma industry is suffering as a result from a mismeasure of uncertainty. Despite promise of molecular revolution and drugs by design, pipelines are dwindling. Pharma companies seek to identify the largest markets they can find, develop products for these customers and boost efficiency of development process. Wrong approach, for two reasons: drug sales notoriously hard to foresee (yields more false precision than true insight), and drug development process is also very difficult to predict. This strategy fails to reduce exposure to negative uncertainty (all the bad things that can happen during drug development), and eliminates much of the exposure to positive uncertainty (serendipity). Pharma's trend of outsourcing may open up possibility for innovators with a greater appreciation of the nuances of science to do a lot better. (Published: 30/07/08)
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Tuesday, July 29, 2008
Quote of the Day
“If I had asked my customers what they wanted, they would have said a faster horse.” - Henry Ford
Sunday, July 27, 2008
When to start - Seth Godin
"The best time to start was last year. The second best time to start is right now." - Seth Godin
Notes:
When to start
Actually, as you've probably guessed, the best time to start was last year. The second best time to start is right now.
Saturday, July 26, 2008
Quote of the Day
"We shape our buildings, and afterwards our buildings shape us." - Churchill
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Friday, July 25, 2008
Nano-machine captures zinc in protein-like jaws - R&D Magazine
Summary:
A team from Berkely Lab generates a protein-like function from a synthetic polymer: two helical peptoids with functional groups at the end, linked together using an unstructured segment. The two-helix bundle can fold in half and bind a zinc ion. Perhaps anitial step toward developing nanostructures that combine the precision of proteins with the ruggedness of non-natural materials. Such foldable polymer bundles could lead to highly accurate sensors capable of operating in harsh environments, or disease-targeting pharmaceuticals that last much longer than today's therapies. (Published: 22/07/08)
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Tuesday, July 22, 2008
Buffett on the Stock Market (1999) - Fortune Magazine
Summary:
Buffet looking back in 1999 at the preceding 34 years and looking at the prospects for the stockmarket over the next 17 years. Preceding 34 years consisted of two contrasting 17 year periods. In first period, DJIA hardly moved; in second period, up nearly 10x. Main difference: interest rates and corporate profits. Interest rates down significantly in after 1982, and healthy corporate profits for period. Superimposed was market psychology. Many investors think next 17y will be more of the same. Buffett says this is unlikely: would require lowering of interest rates, and corporate profits after tax as a percentage of GDP to remain in excess of 6%. Profits cannot grow faster than GDP. Returns over next 17y more likely to be around 6%/year (4% reall return). Buffett on the chances of succesfully riding a wave of innovation: just look what happened to the automobile and aviation industries. Much easier to pick losers than to pick winners. However, key to investing is not assessing how much an industry is going to affect society, or how much it will grow, but rather determining the competitive advantage of any given company and, above all, the durability of that advantage. (Published: 22/11/1999)
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Thursday, July 3, 2008
Monday, June 16, 2008
Manufacturers plan to outsource more R&D - Economist Intelligence Unit
Summary:
A survey reveals that an increasing number of manufacturers are keen to outsource R&D and innovation. The main motivation is skills shortage in design and engineering. To keep pace with the breathtaking pace of product innovation, outsourcing elements of research and development may be the only viable way forward. The biggest barrier to outsourcing innovation is trust, i.e. losing IP to partners or competitors. Better IT technology is needed to prevent this, as well as better communication and an open culture. (Published: 16/06/08)
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Thursday, June 12, 2008
The Manhattan Project Is Underway - Energy Tribune
Summary:
Robert Bryce noting that a Manhatten Project appears to be underway, except that there are no government mandates: huge investments are made in renewable technologies by private investors. Two main difference between previous energy crisis (70s) and now: huge amount of venture capital available, and the amount of new technologies that are being brought to the market as a result. Far better that these risk be taken by the private sector. No government agency can react as quickly as the private sector can. Markets, not governments, are going to determine the pace of our transition to alternative and renewable fuels. (Published: 12/06/08)
Summary:
Wednesday, June 11, 2008
Quote of the Day
"It's such a fine line between stupid and clever." - David St. Hubbins (Spinal Tap)
Tuesday, June 10, 2008
Quote of the Day
"Nothing is impossible. Some things are just less likely than others." - Jonathan Winters
Quote of the Day
"The beginning of knowledge is the discovery of something we do not understand." - Frank Herbert
Wednesday, June 4, 2008
Government Sponsored Versus Private Venture Capital: Canadian Evidence - NBER Working Paper
Summary:
Paper investigating the relative performance of enterprises backed by government-sponsored venture capitalists and private venture capitalists. Results indicate that enterprises financed by government-sponsored venture capitalists underperform on a variety of criteria, including value-creation and innovation. Arises in part from a selection effect and in part from a treatment effect. Results cast doubt on the desirability of certain government interventions in the venture capital market. (Published: 05/08)
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